Speaker: Talking past each other: Ideological silos and research
345 Responses
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Bart Janssen, in reply to
And I reckon changing diet can tend to be explosive
Yeah - make changes gradually :).
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I'm also fascinated by developments in this area. My brother has had a variety of health issues over the years and is now being treated by a doctor (in Oz) who believes that digestive and dietary factors need to be rebalanced for overall improvements. Including in areas such as depression/anxiety. So, my brother is seeing gradual improvements, which we hope will continue.
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Carol Stewart, in reply to
Cheers for that Bart.. very interesting. I've found that starting the day with a bowl of oatmeal and yoghurt seems to be very beneficial for my overall digestive wellbeing (sorry, TMI). I think it's quite good to pay attention to how you feel after eating various foods.
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Moz, in reply to
I've found that starting the day with a bowl of oatmeal and yoghurt seems to be very beneficial
I got interested pretty much the opposite way... via an exclusion diet to reduce the volume and intensity of my farting. The low FODMAP diet seems to be a close summary of what works for me, but I do regularly and deliberately push the edges both for a bit of variety in my diet and because many of the foods I particularly like are outside the restrictions. OTOH, it appears I can tolerate (possibly benefit) from small amounts of some "bad" foods.
Yoghurt and oatmeal, though, not so much. I found it... explosive. But the combination of lactose (makes my gut unhappy) and oats (make my gut unhappy) proved to... make my gut unhappy. And I generally dislike fermented products, which I'm inclined to say is my brain going "hmm, in the past I felt bad after eating things that smell like that".
So I watch the microbiome suggestions with interest, and try them with care. I fear that there's a critical threshold below which there's not enough gut bacteria that can deal with lactose usefully to allow me to deal with lactose at all. Soygurt, BTW, causes the same problem (so does soy in general, which is kinda sad coz I like tempeh and tofu)
Eating straight from the garden I definitely do :)
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Jeremy Andrew, in reply to
BTW they also point out that almost all the “probiotic” foods/pills etc are just large doses of brewers yeast (Saccharomyces) which is kind of pointless and usually quite expensive compared to just eating brewers yeast (which I don’t think is worthwhile either).
Being a home brewer, I get plenty of brewers yeast in my diet, plus plenty of fermented product. :-)
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Rebecca Gray, in reply to
Oh this is a nicer diversion topic.
I find the microbiome stuff fascinating too. Be really interested to see where this research goes in the next few years.
We've had some fermented vegetable experiments in our kitchen lately and I have no idea whether there have been health benefits, but I will say the home-fermented pickles are really tasty so, hell, why not.Prof Julian Crane gave a talk about developments in microbiome research a couple of years ago, and the one slide that I'm sure he KNEW we'd be unable to forget was about how there are DIY kits for carrying out faecal transplantation at home. Apparently the moral of this story may be "don't buy secondhand blenders if you don't know where they've been" :-s
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Bart Janssen, in reply to
but I will say the home-fermented pickles are really tasty so, hell, why not
This is one reason why I'm comfortable suggesting these things. None of the suggestions is inconsistent with generally "good eating" and many are damn tasty.
Moz
via an exclusion diet
a couple of comments, apparently as we get older we tend to lose some ability to process lactose - not a complete loss though. So often folks find reducing but not eliminating works well.
The other comment is I get the feeling a lot of folks try eliminating parts of their diet to deal with some problem or another. And if they feel better they never reintroduce that part of their diet. If the change in diet and feeling better was a coincidence that means they lost some diversity in their diet. While it may not be fun to check I'd personally want to see if reintroducing the food caused the problem again.
I also wonder about some folks (not specifically you Moz) who progressively exclude elements of their diet and end up with a very narrow diet which would probably lead to a less diverse gut microbiome which is generally thought to be less ideal. And yes I am aware some folks have to restrict their diet for real reasons.
It also fascinates me that people are so happy to experiment on themselves. These are really experiments with a sample of one and huge observer bias. I get why people do it but then often those same people are very concerned about scientists or big pharma/business experimenting on them - it's ... odd.
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B Jones, in reply to
You get gut microbiome diversity from gardening, getting your hands dirty. And from eating food straight from the garden.
That's how my partner got toxoplasmosis :-)
I hope youse fellas are all eating unsweetened yoghurt. Your average pottle of fresh n fruity has a lot of sugar in it, and it's thickened with gelatine. I don't know whether or not it gets fermented the way they make it.
This is one of those fields in which there is so much unmet demand and unknowns that there's room for plenty of pseudoscience. People want to believe. There's body politics, health politics, expertise-claiming politics. There's no shortage of crankery in mistreating health conditions with special expensive diets. I'll be taking this cutting edge stuff with a healthy pinch of low-sodium salt substitute before I jump on the bandwagon.
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There seem to be gut-related issues with autism and it is rare to find a person on the spectrum, and even close family members, who do not have some long-standing digestive issues. The MindsforMinds group at Auckland University has been doing some work on this.
I also heard recently, from some authoritative scientific person, that there is also a relationship between lack of breastfeeding and the development of ADHD. I don't want to get into the breastfeeding and guilt thing, but that could indicate another gut microbiome thing going on.
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Hebe, in reply to
From my reading, yoghurt, sauerkraut, kimchi, kefir, miso, tempeh, and natto are some.
I have been looking into the area from the POV of having a stress-depleted immune system and three years of illness, and how to rebuild. I'm cautious about any silver bullet - as much as I would like one - and this path seems promising. -
Hebe, in reply to
We’ve had some fermented vegetable experiments in our kitchen lately and I have no idea whether there have been health benefits, but I will say the home-fermented pickles are really tasty so, hell, why not.
I'd like to but I'm a little jumpy about bad bugs versus good bugs for the body, and how to get the good bugs taking charge. Do you have reliable recipe links?
As for the blender: ewww!
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Russell Brown, in reply to
There seem to be gut-related issues with autism and it is rare to find a person on the spectrum, and even close family members, who do not have some long-standing digestive issues. The MindsforMinds group at Auckland University has been doing some work on this.
It would good to know some non-bogus stuff about this. My older son has uncomfortable – and sometimes socially inappropriate – belching problems.
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People might want to watch Rob Knight's (still a few kiwi vowels) Ted talk.
https://www.ted.com/talks/rob_knight_how_our_microbes_make_us_who_we_are/transcript?language=en
Though I think he would agree that it is a really complicated micro-ecology of interactions in there, so you can't really just swap-out microfauna on the grounds of "this one seems good in isolation" at present. -
Hebe, in reply to
It would good to know some non-bogus stuff about this. My older son has uncomfortable – and sometimes socially inappropriate – belching problems.
See my message for a link on t'other social network.
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Joe Wylie, in reply to
Bear in mind also that while I've read widely I am a plant developmental/molecular biologist and not an expert on the gut microbiome so my opinion is my opinion.
So when you posted here a couple of years back about "Make cows burp less by making them more efficient (better grass or better bacteria) and the farmer gains", you'd have been speaking as one of the grass guys.
It also fascinates me that people are so happy to experiment on themselves. These are really experiments with a sample of one and huge observer bias. I get why people do it but then often those same people are very concerned about scientists or big pharma/business experimenting on them - it's ... odd.
Informed consent?
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Bart Janssen, in reply to
you’d have been speaking as one of the grass guys
heh the plant side of that idea is much closer to my specialty but even then it isn't an area where I'd be comfortable writing a grant today but I would have the background to read the literature and understand it well enough to probably write a decent grant after a month or so of heavy reading. I'd almost certainly try and get a collaborator who is a real grass expert though.
This http://www.sciencedirect.com/science/article/pii/S1369526613001672 is my real focus.
The animal side of that is far enough outside my expertise that I'd never try and write a grant to do that work but I'd be comfortable that I'd understand any seminar on the subject.
It really is a problem with any scientific expertise nowadays. We are all very specialised, we can usually read and understand (and potentially explain) much wider. But the trap in some fields is you may not know the sometimes very technical weaknesses in any given research.
While I do describe myself now as a plant developmental biologist - I trained as a molecular biologist (gene jockey) which means I'm comfortable with most things about DNA and RNA but often less comfortable with the organism the DNA came from :).
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Bart Janssen, in reply to
Informed consent?
Hmmm yeah kinda. Informed usually means some good understand of all the risks and expected outcomes. I somehow doubt everyone who experiments on themselves is as informed as an ethics committee would normally require if they were subjects in a scientific study.
But yeah it's their body to do with as they wish.
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Bart Janssen, in reply to
There seem to be gut-related issues with autism and it is rare to find a person on the spectrum, and even close family members, who do not have some long-standing digestive issues. The MindsforMinds group at Auckland University has been doing some work on this.
It would good to know some non-bogus stuff about this. My older son has uncomfortable – and sometimes socially inappropriate – belching problems.
A question for both of you. Do people on the spectrum tend to want have more diverse or less diverse diets?
I would have guessed they'd prefer more predictable (less diverse) eating habits. If that's true you might predict they'd have less diverse gut biomes. I guess my feeling from what I've read thus far is I'd probably be inclined to treat gut problems now by adding to the diet rather than subtracting - that is very much a personal guess though.
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Carol Stewart, in reply to
Exactly, it's the 'informed' bit that is the problem.
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The n=1 thing is a problem too.
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Rosemary McDonald, in reply to
Oh this is a nicer diversion topic.
And I'm going to risk it going to shit...a bit..
About 23 years ago a friend, her hubby and nine month old daughter picked up a lovely dose of Cryptosporidium
Parents were on the mend, but not quite well enough to care for the baby...who had the worst case of nappy rash (courtesy of the bug) I have almost ever seen. Auntie Rosemary to the rescue...and by far the best treatment was no nappy, baking soda baths and some time spent with affected part in (filtered) sunlight. Two days and she came right...but..despite my bestest precautions...you guessed it...the bug got me.
To be honest...the screaming shits for four weeks was almost not as debilitating as it sounds...I simply couldn't eat anything remotely solid/fatty/meaty. I could drink fluids, and milk, but anything solid...10 minutes and it was gone. This reaction to many solid foods continued for at least six months.
I was able to function very well. Surprisingly, for someone who enjoys a good feed. I just drank heaps, ate when it was convenient(work it out...but timing was everything) and lost gobs and gobs and gobs of weight. Which, of course, I have regained much of in the ensuing years...not that it bothers me. I still can have a reaction to some red meats..
I find the whole area of gut flora (and fauna) fascinating, and I think we just might be on to something...especially if we each could figure out our own personal nutrition uptake controlling gut bug.
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Joe Wylie, in reply to
While I do describe myself now as a plant developmental biologist - I trained as a molecular biologist (gene jockey) which means I'm comfortable with most things about DNA and RNA but often less comfortable with the organism the DNA came from :).
Thanks Bart, that certainly rang a bell - and here it is, a few paragraphs into Chapter One of my very favourite science book, Colin Tudge's tour de force of taxonomy, The Variety of Life:
Indeed a breed of molecular biologists has grown up who actually cannot tell the difference between a frog and a toad—or, indeed, when you boil it down, between a toad and a toadstool—because, quite simply, the difference does not seem to matter to them. DNA is DNA is DNA.
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Hilary Stace, in reply to
Many people on the spectrum have quite limited diets. But that could be because of some natural distrust of certain foods and their effects.
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Hebe, in reply to
especially if we each could figure out our own personal nutrition uptake controlling gut bug.
Yes!
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Russell Brown, in reply to
A question for both of you. Do people on the spectrum tend to want have more diverse or less diverse diets?
I would have guessed they’d prefer more predictable (less diverse) eating habits. If that’s true you might predict they’d have less diverse gut biomes. I guess my feeling from what I’ve read thus far is I’d probably be inclined to treat gut problems now by adding to the diet rather than subtracting – that is very much a personal guess though.
As Hilary says, it’s not as simple as choosing. Believe it or not, colour can be a big factor in acceptability. Our older son has a relatively “normal” diet (he struggles hard to get salads down, on account of texture), while our younger son has a very limited, bready diet (mainly pizza with cheese, olive oil and garlic, but not sauce; cheesy bagels; Nutrigrain; milk). It’s not ideal, but eventually you realise a war on your kid’s nature is not ideal either. Sometimes we get him to take a supplement, but swallowing those is hard.
So adding to the diet is hard. Suggestions on covert (not in the sense that we’d lie to him, just easily acceptable) diet diversity are very welcome.
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